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HBV Mutation Detail Information

> L528M Search Result


Mutation Information
Mutation Site L528M
Mutation Type Amino acid level
Gene/Protein/Region Type P
Relevant Drug lamivudine (LAM)
Literature Information
PubMed PMID 11480792
Disease Chronic hepatitis B
Published Year 2001
Journal Journal of gastroenterology
Title Efficacy and tolerability of long-term therapy using high lamivudine doses for the treatment of chronic hepatitis B.
Author Da Silva LC,Pinho JR,Sitnik R,Da Fonseca LE,Carrilho FJ
Evidence The YMDD mutation was detected in 12 nonresponder patients (9 YVDD, 2 YIDD, and 1 mixed population Y(V/I)DD), generally associated with the L528M mutation.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation