HBV Mutation Detail Information

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Mutation Information
Mutation Site T184C
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug entecavir (ETV)
Literature Information
PubMed PMID 30202825
Disease HBV infection
Published Year 2018
Journal Hepatology communications
Title Discovery of the Novel Entecavir-Resistant Hepatitis B Virus Reverse Transcriptase A181C Substitution From an Integrated Genotypic Analysis.
Author Rose RE,Hernandez D,Falk PJ,Ericson K,Zhou N,Thiry A,McPhee F
Evidence ETVr substitutions at rtT184 (rtT184C/G/I/S) have been shown to exhibit low‐level ETVr and have only been observed in combination with other ETVr substitutions in patients with virologic breakthrough.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation