HBV Mutation Detail Information

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Mutation Information

Mutation Site	M204I
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	lamivudine (LAM)
Country	Japan

Literature Information

PubMed PMID	25817219
Disease	Chronic hepatitis B
Published Year	2015
Journal	Journal of hepatology
Title	Characterization of novel entecavir resistance mutations.
Author	Hayashi S,Murakami S,Omagari K,Matsui T,Iio E,Isogawa M,Watanabe T,Karino Y,Tanaka Y
Evidence	The analysis also identified multiple mutations in the reverse transcriptase (RT) that occurred before and after ETV treatment. At baseline (0 month), when the patient was refractory to LAM treatment, serum HBV contained the well-documented LAM resistance mutations rtV173L, rtL180M, and rtM204I

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation