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Mutation Information
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Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204I+rt.L180M;rt.M204V+rt.L180M |
|
Genotype/Subtype
|
A;E |
|
Country
|
Gabon |
Literature Information
|
PubMed PMID
|
26764909
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2016 |
|
Journal
|
PloS one |
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Title
|
Broad Range of Hepatitis B Virus (HBV) Patterns, Dual Circulation of Quasi-Subgenotype A3 and HBV/E and Heterogeneous HBV Mutations in HIV-Positive Patients in Gabon. |
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Author
|
Bivigou-Mboumba B,François-Souquière S,Deleplancque L,Sica J,Mouinga-Ondémé A,Amougou-Atsama M,Chaix ML,Njouom R,Rouet F |
|
Evidence
|
Regarding RAMs, the mutation M204V/I, associated with the compensatory mutation L180M, was significantly more common in genotype HBV/A (9/19, 47.4%) than in genotype HBV/E (0/9, 0%) (Yate’s corrected χ2, P = .04) (Fig 6, Table 2).
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HBV Mutation Detail Information