Mutation Information
Mutation Site
|
P177G |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Viral Reference
|
U95551
|
Relevant Drug
|
tenofovir (TDF) |
Literature Information
PubMed PMID
|
23261845
|
Published Year
|
2013 |
Journal
|
Antiviral research |
Title
|
The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovir. |
Author
|
Qin B,Budeus B,Cao L,Wu C,Wang Y,Zhang X,Rayner S,Hoffmann D,Lu M,Chen X |
Evidence
|
The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovir.
|
|
|