HBV Mutation Detail Information

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Mutation Information

Mutation Site	H508L
Mutation Type	Amino acid level
Gene/Protein/Region Type	P
Country	Argentine

Literature Information

PubMed PMID	16757620
Disease	Chronic hepatitis B
Published Year	2006
Journal	Journal of clinical microbiology
Title	Unusual naturally occurring humoral and cellular mutated epitopes of hepatitis B virus in a chronically infected argentine patient with anti-HBs antibodies.
Author	Cuestas ML,Mathet VL,Ruiz V,Minassian ML,Rivero C,Sala A,Corach D,Alessio A,Pozzati M,Frider B,Oubiña JR
Evidence	Pol-mutated epitopes (the overlapped region within the S protein is underlined) were observed within amino acids 455 to 463 (L463S in clone 1) and 504 to 512 (P509H in clone 1 and H508L in clone 5) for MHC-I peptides and within amino acids 503 to 517 (P509H in clone 1 and H508L in clone 5) for the overlapped MHC-II peptide.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation