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Mutation Information
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Mutation Site
|
V207M |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Combined Mutation
|
rt.V207I+rt.V207M;rt.S213T+rt.V207M;rt.L229V+rt.V207M;rt.I233V+rt.V207M;rt.S256G+rt.S213T+rt.V207M;rt.V207M+rt.V207I+rt.M204V+rt.L180M;rt.S256G+rt.S213T+rt.V207M+rt.I187V;rt.V207M+rt.V207I+rt.K212T;rt.V207M+rt.V253I;rt.L229V+rt.V207M+rt.L235V;rt.V207M+rt.V207I |
|
Relevant Drug
|
lamivudine (LAM);adefovir dipivoxil (ADV);tenofovir (TDF);entecavir (ETV) |
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Country
|
Vietnam |
Literature Information
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PubMed PMID
|
32708399
|
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Disease
|
Chronic hepatitis B
|
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Published Year
|
2020 |
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Journal
|
Diagnostics (Basel, Switzerland) |
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Title
|
COLD-PCR Method for Early Detection of Antiviral Drug-Resistance Mutations in Treatment-Naive Children with Chronic Hepatitis B. |
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Author
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Phung TTB,Chu SV,Vu ST,Pham HT,Nguyen HM,Nguyen HD,Le NT,Nguyen DV,Truong PT,Vu VTT,Nguyen ATV |
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Evidence
|
Single-point mt associated to LMV and ADF resistance were detected in 59.9% of the tested children with rtV207M (38.0%) and rtN238T (9.9%) being the most frequent.
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HBV Mutation Detail Information