|
Mutation Information
|
Mutation Site
|
N139D |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
30906435
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2019 |
|
Journal
|
Experimental and therapeutic medicine |
|
Title
|
Viral quasispecies of hepatitis B virus in patients with YMDD mutation and lamivudine resistance may not predict the efficacy of lamivudine/adefovir rescue therapy. |
|
Author
|
Wang C,Yu S,Zhang Y,Zhang M,Lv L,Huang C,Li X,Li J,Zhang Z |
|
Evidence
|
Common and frequent mutations identified in the cohort of the present study included rtL80V/I, rtV84M, rtL91I, rtN118H/D/T, rtT128A, rtL180M, rtT184L/S/A, rtV191I, rtS202G, rtV207I/M, rtS213T, rtQ215P/S/H, rtL229V/M/W/F, rtS256G/C, and rtN337H/T, as presented in Table II. I
|
|
|
HBV Mutation Detail Information