|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
D |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
18008227
|
|
Disease
|
HBV infection
|
|
Published Year
|
2007 |
|
Journal
|
The Journal of infectious diseases |
|
Title
|
Hepatitis B virus containing the I233V mutation in the polymerase reverse-transcriptase domain remains sensitive to inhibition by adefovir. |
|
Author
|
Curtis M,Zhu Y,Borroto-Esoda K |
|
Evidence
|
This patient had previously been treated with lamivudine for 3 years and had developed lamivudine-resistant HBV (rtL180M/M204V) and liver decompensation.
|
|
|
HBV Mutation Detail Information