HBV Mutation Detail Information

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Mutation Information

Mutation Site	S202G
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	rt.M204V+rt.S202G+rt.L180M
Relevant Drug	entecavir (ETV)
Country	China

Literature Information

PubMed PMID	20580309
Disease	HBV infection
Published Year	2010
Journal	Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Title	Acute hepatitis B infection associated with drug-resistant hepatitis B virus.
Author	Xu Z,Liu Y,Xu T,Chen L,Si L,Wang Y,Ren X,Zhong Y,Zhao J,Xu D
Evidence	Direct PCR sequencing showed that 14 samples (7.0%) were positive for drug-resistant HBV variants, comprised of 11 with the lamivudine-resistant pattern rtM204I and/or rtM204V in the presence and absence of compensatory mutations rtL80I, rtV173L, and rtL180M; two with the adefovir-resistant pattern rtA181V; and one with the entecavir-resistant pattern rtL180M+rtS202G+rtM204V.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation