HBV Mutation Detail Information

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Mutation Information
Mutation Site S567A
Mutation Type Amino acid level
Gene/Protein/Region Type P
Relevant Drug famciclovir (FCV)
Literature Information
PubMed PMID 10589947
Disease Chronic hepatitis B
Published Year 1999
Journal Transplantation
Title Famciclovir treatment of chronic hepatitis B in heart transplant recipients: a prospective trial.
Author Wedemeyer H,Böker KH,Pethig K,Petzold DR,Flemming P,Tillmann HL,Vollmar J,Bastürk M,Goldmann E,Griffin KE,Haverich A,Manns MP
Evidence Three patients developed virological breakthrough on famciclovir after 7, 8, and 26 months of treatment showing HBV-polymerase amino acid changes L528 M, S567A, and I581K, respectively.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation