HBV Mutation Detail Information

> N236T Search Result


Mutation Information
Mutation Site N236T
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug adefovir (ADV);lamivudine (LAM)
Literature Information
PubMed PMID 14642631
Disease HBV infection
Published Year 2003
Journal Journal of hepatology
Title Selection of a hepatitis B virus strain resistant to adefovir in a liver transplantation patient.
Author Villeneuve JP,Durantel D,Durantel S,Westland C,Xiong S,Brosgart CL,Gibbs CS,Parvaz P,Werle B,Trépo C,Zoulim F
Evidence RESULTS: Sequence analyses of the HBV polymerase gene revealed a sequential selection of lamivudine resistance mutations L180M+M204V, followed by a reversion to wild-type, and subsequently the selection of a novel adefovir resistance mutation N236T.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation