Mutation Information
Mutation Site
|
D7A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Combined Mutation
|
rt.S78T+rt.D7A+rt.L4I+rt.E10D;rt.D7A+rt.L4I+rt.E10D;rt.S54Y+rt.I53N+rt.D7A+rt.L4I+rt.E10D;rt.I91L+rt.H90N+rt.S54Y+rt.I53N+rt.D7A+rt.L4I+rt.E10D |
Viral Reference
|
AY741797.1
|
Country
|
Germany |
Literature Information
PubMed PMID
|
28392234
|
Disease
|
HBV infection
|
Published Year
|
2017 |
Journal
|
Journal of hepatology |
Title
|
Selection of the highly replicative and partially multidrug resistant rtS78T HBV polymerase mutation during TDF-ETV combination therapy. |
Author
|
Shirvani-Dastgerdi E,Winer BY,Celià-Terrassa T,Kang Y,Tabernero D,Yagmur E,Rodríguez-Frías F,Gregori J,Luedde T,Trautwein C,Ploss A,Tacke F |
Evidence
|
Table 1
|
|
|