|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
adefovir (ADV);entecavir (ETV) |
|
Country
|
Germany |
Literature Information
|
PubMed PMID
|
23408582
|
|
Disease
|
HBV infection
|
|
Published Year
|
2013 |
|
Journal
|
Journal of medical virology |
|
Title
|
High frequency of complex mutational patterns in lamivudine resistant hepatitis B virus isolates. |
|
Author
|
Neumann-Fraune M,Beggel B,Pfister H,Kaiser R,Verheyen J |
|
Evidence
|
Both mutations, especially mutation rtM204V, were most often accompanied by compensatory mutations rtV173L and rtL180M but also by mutations conferring entecavir (n = 5) or adefovir resistance (n = 4).
|
|
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HBV Mutation Detail Information