HBV Mutation Detail Information

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Mutation Information
Mutation Site N236T
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug adefovir (ADV)
Literature Information
PubMed PMID 18537180
Disease Chronic hepatitis B
Published Year 2008
Journal Hepatology (Baltimore, Md.)
Title The antiviral drug selected hepatitis B virus rtA181T/sW172* mutant has a dominant negative secretion defect and alters the typical profile of viral rebound.
Author Warner N,Locarnini S
Evidence In contrast, rtA181T/sW172* was detected alone in 11%, and in combination with rtN236T in 7% of ADV‐resistant cases (18% of total ADV‐resistant cases) (Table 2).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation