Mutation Information
Mutation Site
|
T184I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Genotype/Subtype
|
C |
Viral Reference
|
AB033550
|
Country
|
Japan |
Literature Information
PubMed PMID
|
25061278
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2014 |
Journal
|
Drug design, development and therapy |
Title
|
Virologic breakthrough in a patient with chronic hepatitis B by combination treatment with tenofovir disoproxil fumarate and entecavir. |
Author
|
Suzuki F,Sezaki H,Akuta N,Suzuki Y,Kawamura Y,Hosaka T,Kobayashi M,Saitoh S,Arase Y,Ikeda K,Kobayashi M,Watahiki S,Mineta R,Suzuki Y,Kumada H |
Evidence
|
At the start of combination therapy, amino acid substitutions of the reverse transcriptase (rt) gene, rtL180M, rtT184I/M, and rtM204V, were detected.
|
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