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HBV Mutation Detail Information

> M250V Search Result


Mutation Information
Mutation Site M250V
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.L180M+rt.M204V+rt.I169T+rt.M250V
Relevant Drug adefovir (ADV)
Literature Information
PubMed PMID 16673294
Published Year 2006
Journal Seminars in liver disease
Title Antiviral drug resistance: clinical consequences and molecular aspects.
Author Bartholomeusz A,Locarnini SA
Evidence Modeling of the group1 ETVresistance mutations indicates that residues rtM250VrtI169T will affect the elongating DNA strand.These mutations act cooperatively for high-level ETVresistance
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation