HBV Mutation Detail Information

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Mutation Information

Mutation Site	M204V
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Amino acid_Mutation	A739G
Genotype/Subtype	A
Relevant Drug	lamivudine (LAM)

Literature Information

PubMed PMID	18606836
Disease	Chronic hepatitis B
Published Year	2008
Journal	Antimicrobial agents and chemotherapy
Title	Rolling circle amplification, a powerful tool for genetic and functional studies of complete hepatitis B virus genomes from low-level infections and for directly probing covalently closed circular DNA.
Author	Margeridon S,Carrouée-Durantel S,Chemin I,Barraud L,Zoulim F,Trépo C,Kay A
Evidence	Only the genomes from the last biopsy specimen obtained after the emergence of lamivudine resistance contained the lamivudine resistance-associated mutations rtL180M and rtM204V ("rt" indicates reverse transcriptase domain).

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation