HBV Mutation Detail Information

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Mutation Information

Mutation Site	V173L
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT

Literature Information

PubMed PMID	17438047
Published Year	2007
Journal	Antimicrobial agents and chemotherapy
Title	The L80I substitution in the reverse transcriptase domain of the hepatitis B virus polymerase is associated with lamivudine resistance and enhanced viral replication in vitro.
Author	Warner N,Locarnini S,Kuiper M,Bartholomeusz A,Ayres A,Yuen L,Shaw T
Evidence	Numerous amino acid substitutions in rt besides rtM204I/V/S, rtL180M, and rtV173L have since been detected by genotyping of clinical HBV isolates from patients undergoing long-term LMV treatment.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation