HBV Mutation Detail Information

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Mutation Information

Mutation Site	M204I
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT

Literature Information

PubMed PMID	14752824
Disease	Chronic hepatitis B
Published Year	2004
Journal	Hepatology (Baltimore, Md.)
Title	Identification of HBV DNA sequences that are predictive of response to lamivudine therapy.
Author	Ciancio A,Smedile A,Rizzetto M,Lagget M,Gerin J,Korba B
Evidence	A change from p91I to p91L occurred in 1 breakthrough patient (#13) at month 11 of treatment (the first sample in which the nested PCR reaction could detect HBV DNA during therapy), 1 month before virological rebound (as defined by the Monitor PCR assay) and the emergence of pM204I

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation