|
Mutation Information
|
Mutation Site
|
V173L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
A;D |
|
Relevant Drug
|
lamivudine (LAM);telbivudine (LDT);entecavir (ETV);clevudine (CLV) |
|
Country
|
Ethiopia |
Literature Information
|
PubMed PMID
|
27354181
|
|
Disease
|
HBV-HIV coinfection;
HBV infection
|
|
Published Year
|
2017 |
|
Journal
|
Antiviral therapy |
|
Title
|
HIV therapy with unknown HBV status is responsible for higher rate of HBV genome variability in Ethiopia. |
|
Author
|
Belyhun Y,Maier M,Liebert UG |
|
Evidence
|
RESULTS: In 34 out of 161 study subjects (21.1%) HBV drug resistance mutations (DRMs) were detected with a frequency of 3.1% rtL80F/I, 0.6% rtA181V, 1.2% rtT184S, 6.2% rtV173L, 10.6% rtL180M, 10.6% rtM204V/I and 8.1% rtI233V.
|
|
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HBV Mutation Detail Information