|
Mutation Information
|
Mutation Site
|
N236T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
adefovir (ADV) |
Literature Information
|
PubMed PMID
|
18752330
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2008 |
|
Journal
|
Hepatology (Baltimore, Md.) |
|
Title
|
Long-term efficacy and safety of adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B. |
|
Author
|
Marcellin P,Chang TT,Lim SG,Sievert W,Tong M,Arterburn S,Borroto-Esoda K,Frederick D,Rousseau F |
|
Evidence
|
Adefovir resistance mutations A181V or N236T developed in 13 LTSES patients; the first observation was at study week 195.
|
|
|
HBV Mutation Detail Information