|
Mutation Information
|
Mutation Site
|
I224V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Amino acid_Mutation
|
A799G |
|
Viral Reference
|
EU871982.1
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
24788140
|
|
Disease
|
Hepatocellular carcinoma
|
|
Published Year
|
2014 |
|
Journal
|
PloS one |
|
Title
|
Novel natural mutations in the hepatitis B virus reverse transcriptase domain associated with hepatocellular carcinoma. |
|
Author
|
Wu Y,Gan Y,Gao F,Zhao Z,Jin Y,Zhu Y,Sun Z,Wu H,Chen T,Wang J,Sun Y,Fan C,Xiang Y,Qian G,Groopman JD,Gu J,Tu H |
|
Evidence
|
A799G and T1055A are missense mutations resulting in aa substitutions of I224V and M309K, and A987G is a synonymous mutation.
|
|
|
HBV Mutation Detail Information