Mutation Information
Mutation Site
|
M204V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Viral Reference
|
AM282986
|
Literature Information
PubMed PMID
|
24814823
|
Published Year
|
2014 |
Journal
|
Current opinion in virology |
Title
|
Nucleoside/nucleotide analog inhibitors of hepatitis B virus polymerase: mechanism of action and resistance. |
Author
|
Menéndez-Arias L,Álvarez M,Pacheco B |
Evidence
|
Major mutational patterns conferring nucleoside/nucleotide analog resistance include the combinations rtL180M/rtM204(I/V) (for lamivudine, entecavir, telbivudine and clevudine) and rtA181V/rtN236T (for adefovir and tenofovir).
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