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Mutation Information
|
Mutation Site
|
M204I |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Combined Mutation
|
s.W196L+rt.M204I |
Literature Information
|
PubMed PMID
|
22082274
|
|
Disease
|
HBV associated liver disease
|
|
Published Year
|
2011 |
|
Journal
|
Biochemistry. Biokhimiia |
|
Title
|
Antiviral resistance mutations potentiate HBV surface antigen-induced transcription of hfgl2 prothrombinase gene. |
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Author
|
Li W,Han M,Li Y,Chen D,Luo X,Ning Q |
|
Evidence
|
To investigate whether the nucleotide (nucleoside)-induced resistant mutations of HBs potentiate transcription of hfgl2 prothrombinase gene, we generated two mutant HB expression constructs harboring rtM204V/sI195M or rtM204I/sW196L mutations.
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HBV Mutation Detail Information