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Mutation Information
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Mutation Site
|
I515L |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Viral Reference
|
AF282918.1
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Literature Information
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PubMed PMID
|
19812261
|
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Published Year
|
2010 |
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Journal
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The Journal of general virology |
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Title
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Biological significance of amino acid substitutions in hepatitis B surface antigen (HBsAg) for glycosylation, secretion, antigenicity and immunogenicity of HBsAg and hepatitis B virus replication. |
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Author
|
Wu C,Zhang X,Tian Y,Song J,Yang D,Roggendorf M,Lu M,Chen X |
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Evidence
|
In this study, the substitutions sK122I, sT123N and sK160N in HBsAg led to the substitutions rtQ476H, rtN477K and rtI515L in the polymerase.
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HBV Mutation Detail Information