|
Mutation Information
|
Mutation Site
|
P177G |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
A;B;C;D;H;I |
|
Relevant Drug
|
tenofovir (TDF) |
Literature Information
|
PubMed PMID
|
33238650
|
|
Published Year
|
2020 |
|
Journal
|
Viruses |
|
Title
|
Global Occurrence of Clinically Relevant Hepatitis B Virus Variants as Found by Analysis of Publicly Available Sequencing Data. |
|
Author
|
Velkov S,Protzer U,Michler T |
|
Evidence
|
Two other mutations have been associated with tenofovir resistance, P177G and F249A; however, these mutations were created by site-directed mutagenesis in vitro, and it is unclear if they are found in patient-derived circulating virus.
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HBV Mutation Detail Information