HBV Mutation Detail Information

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Mutation Information
Mutation Site A181V
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug adefovir (ADV)
Country China
Literature Information
PubMed PMID 20580309
Disease HBV infection
Published Year 2010
Journal Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Title Acute hepatitis B infection associated with drug-resistant hepatitis B virus.
Author Xu Z,Liu Y,Xu T,Chen L,Si L,Wang Y,Ren X,Zhong Y,Zhao J,Xu D
Evidence Direct PCR sequencing showed that 14 samples (7.0%) were positive for drug-resistant HBV variants, comprised of 11 with the lamivudine-resistant pattern rtM204I and/or rtM204V in the presence and absence of compensatory mutations rtL80I, rtV173L, and rtL180M; two with the adefovir-resistant pattern rtA181V; and one with the entecavir-resistant pattern rtL180M+rtS202G+rtM204V.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation