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Mutation Information
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Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Viral Reference
|
AB179747;
AY090460;
AF160501;
X75663;
X75664;
X75657;
X02496;
X65257;
V00867;
AB033556;
D00330;
D00329;
X70185;
X02763;
M57663 |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
22170539
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2012 |
|
Journal
|
Journal of medical virology |
|
Title
|
Discrepancy of potential antiviral resistance mutation profiles within the HBV reverse transcriptase between nucleos(t)ide analogue-untreated and -treated patients with chronic hepatitis B in a hospital in China. |
|
Author
|
Li XG,Liu BM,Xu J,Liu XE,Ding H,Li T |
|
Evidence
|
The classical primary drug resistance and secondary/compensatory mutations were only detected at seven sites (rtL80, rtI169, rtL180, rtA181, rtT184, rtM204, and rtN236) in NA-treated patients.
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HBV Mutation Detail Information