|
Mutation Information
|
Mutation Site
|
A546V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
P |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
10682123
|
|
Disease
|
HBV infection
|
|
Published Year
|
1999 |
|
Journal
|
Antiviral therapy |
|
Title
|
Analysis of hepatitis B virus quasispecies changes during emergence and reversion of lamivudine resistance in liver transplantation. |
|
Author
|
Cane PA,Mutimer D,Ratcliffe D,Cook P,Beards G,Elias E,Pillay D |
|
Evidence
|
Other changes associated with lamivudine resistance in some patients were V509I, A546V, S565A and A568T.
|
|
|
HBV Mutation Detail Information