|
Mutation Information
|
Mutation Site
|
I169T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
entecavir (ETV) |
Literature Information
|
PubMed PMID
|
18070286
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2007 |
|
Journal
|
Journal of viral hepatitis |
|
Title
|
Hepatitis B virus polymerase variants associated with entecavir drug resistance in treatment-naive patients. |
|
Author
|
Jardi R,Rodriguez-Frias F,Schaper M,Ruiz G,Elefsiniotis I,Esteban R,Buti M |
|
Evidence
|
The aim of this study was to determine the prevalence of HBV variants associated with ETV resistance (rtI169T, rtT184G, rtS202I, rtM250V) in naive patients before and during lamivudine therapy.
|
|
|
HBV Mutation Detail Information