|
Mutation Information
|
Mutation Site
|
T184G |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204I+rt.L180M+rt.M204V+rt.S202I+rt.T184G |
|
Relevant Drug
|
adefovir (ADV);lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
16673294
|
|
Published Year
|
2006 |
|
Journal
|
Seminars in liver disease |
|
Title
|
Antiviral drug resistance: clinical consequences and molecular aspects. |
|
Author
|
Bartholomeusz A,Locarnini SA |
|
Evidence
|
Modeling of the second group of ETVresistance mutations (rtT184G+tS202I+tM204V+tL180M), reveals an altered geometry of the poly-merase nucleotide binding pocket near the YMDD site
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HBV Mutation Detail Information