|
Mutation Information
|
Mutation Site
|
M204I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
C |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
21734806
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2011 |
|
Journal
|
World journal of gastroenterology |
|
Title
|
Long-term effects of lamivudine treatment in Japanese chronic hepatitis B patients. |
|
Author
|
Murata M,Furusyo N,Unno M,Ogawa E,Toyoda K,Taniai H,Ohnishi H,Hayashi J |
|
Evidence
|
AIM: To analyze the association between the emergence of tyrosine-methionine-asparatate-asparatate (YMDD) mutants (reverse transcription; rtM204I/V) and deterioration of liver function during long-term lamivudine treatment of Japanese patients withChronic hepatitis Bvirus (HBV) infection.
|
|
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HBV Mutation Detail Information