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Mutation Information
|
Mutation Site
|
V173L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
Literature Information
|
PubMed PMID
|
20937597
|
|
Disease
|
HBV infection
|
|
Published Year
|
2010 |
|
Journal
|
Bioinformatics (Oxford, England) |
|
Title
|
A classification model for G-to-A hypermutation in hepatitis B virus ultra-deep pyrosequencing reads. |
|
Author
|
Reuman EC,Margeridon-Thermet S,Caudill HB,Liu T,Borroto-Esoda K,Svarovskaia ES,Holmes SP,Shafer RW |
|
Evidence
|
Among hypermutated UDPS sequence reads, the G → A mutations M204I (7.6%) and A181T (2.9%) were the most common drug-resistance mutations, followed by M204V (0.03%), S202G (0.03%), M250V (0.02%), V173L (0.01%) and T184I (0.01%), which are not caused by G → A substitutions.
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HBV Mutation Detail Information