Mutation Information
Mutation Site
|
A181V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Genotype/Subtype
|
C |
Relevant Drug
|
adefovir (ADV) |
Country
|
China |
Literature Information
PubMed PMID
|
22585719
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2012 |
Journal
|
Journal of medical virology |
Title
|
Factors influencing inadequate or suboptimal response to adefovir with or without genotypic resistance. |
Author
|
Zhou X,Kuang X,Fan K,Zhang C,Deng G,Wang H,Wang Y |
Evidence
|
Seventy-six patients (47.2%) were found to carry the rtA181V/T/S or rtN236T residue substitution, and most of them had viral rebound.
|
|
|