HBV Mutation Detail Information

> M250S Search Result

Mutation Information

Mutation Site	M250S
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	D
Relevant Drug	lamivudine (LAM);entecavir (ETV)

Literature Information

PubMed PMID	20169198
Published Year	2010
Journal	PloS one
Title	Mechanistic characterization and molecular modeling of hepatitis B virus polymerase resistance to entecavir.
Author	Walsh AW,Langley DR,Colonno RJ,Tenney DJ
Evidence	M250 substitutions that were smaller than methionine and replicated well, M250A/G/S/T/C/D/E/Q/N/V/L/I, were all resistant.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation