|
Mutation Information
|
Mutation Site
|
Q215P |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
A;B;C;D |
|
Relevant Drug
|
lamivudine (LAM);adefovir dipivoxil (ADV) |
|
Country
|
China;Italy;India;Turkey |
Literature Information
|
PubMed PMID
|
29713126
|
|
Published Year
|
2018 |
|
Journal
|
World journal of gastroenterology |
|
Title
|
Naturally occurring hepatitis B virus reverse transcriptase mutations related to potential antiviral drug resistance and liver disease progression. |
|
Author
|
Choi YM,Lee SY,Kim BJ |
|
Evidence
|
A total of 26 types of RT mutations, including rtS53N, rtT54N, rtL82M, rtV84M, rtS85A, rtI91L, rtY126C, rtT128I/N, rtN139D, rtW153Q, rtF166L, rtV191I, rtA200V, rtV207I, rtS213T, rtV214A, rtQ215P/S, rtL217R, rtE218D, rtF221Y, rtL229G/V/W, rtI233V, rtP237H, rtN238D/S/T, rtY245H, and rtS/C256G, are considered putative drug resistance mutations (Category 3) (Table (Table11)
|
|
|
HBV Mutation Detail Information