Mutation Information
Mutation Site
|
S259A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Combined Mutation
|
rt.S259A+rt.M250V+rt.M204V+rt.L180M+rt.L164M+rt.V142E+rt.T128I |
Genotype/Subtype
|
D |
Relevant Drug
|
lamivudine (LAM);adefovir dipivoxil (ADV);entecavir (ETV) |
Country
|
Rome |
Literature Information
PubMed PMID
|
19442845
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2009 |
Journal
|
Journal of virological methods |
Title
|
A sensitive direct sequencing assay based on nested PCR for the detection of HBV polymerase and surface glycoprotein mutations. |
Author
|
Vincenti D,Solmone M,Garbuglia AR,Iacomi F,Capobianchi MR |
Evidence
|
Table 1
|
|
|