|
Mutation Information
|
Mutation Site
|
N236T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204I+rt.N236T;rt.A181V+rt.N236T |
|
Genotype/Subtype
|
B;D |
|
Relevant Drug
|
adefovir (ADV) |
Literature Information
|
PubMed PMID
|
19231002
|
|
Clinical information
|
Yes
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2009 |
|
Journal
|
Journal of hepatology |
|
Title
|
Entecavir shows limited efficacy in HBeAg-positive hepatitis B patients with a partial virologic response to adefovir therapy. |
|
Author
|
Reijnders JG,Pas SD,Schutten M,de Man RA,Janssen HL |
|
Evidence
|
TABLE 1
|
|
|
HBV Mutation Detail Information