Mutation Information
Mutation Site
|
A181V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Viral Reference
|
AB713528
|
Relevant Drug
|
lamivudine (LAM);telbivudine (LDT);adefovir dipivoxil (ADV);entecavir (ETV) |
Country
|
Indonesian |
Literature Information
PubMed PMID
|
27492206
|
Disease
|
HBV infection
|
Published Year
|
2016 |
Journal
|
The Kobe journal of medical sciences |
Title
|
Different Variants in Reverse Transcriptase Domain Determined by Ultra-deep Sequencing in Treatment-naïve and Treated Indonesian Patients Infected with Hepatitis B Virus. |
Author
|
Wasityastuti W,Yano Y,Widasari DI,Yamani LN,Ratnasari N,Heriyanto DS,Okada R,Tanahashi T,Murakami Y,Azuma T,Hayashi Y |
Evidence
|
Primary and secondary NA resistance at nine hotspots (rtI169T, rtV173L, rtL180M/I, rtA181T/V, rtT184A/S, rtS202G/I, rtM204V, rtN236T and rtM250V) was investigated using ultra-deep sequencing in treatment naïve and treated Indonesian patients infected with HBV.
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