HBV Mutation Detail Information

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Mutation Information

Mutation Site	R488Q
Mutation Type	Amino acid level
Gene/Protein/Region Type	P
Country	Germany

Literature Information

PubMed PMID	9425945
Disease	Fulminant hepatitis B; Liver cirrhosis
Published Year	1998
Journal	Hepatology (Baltimore, Md.)
Title	Hepatitis B virus with antigenically altered hepatitis B surface antigen is selected by high-dose hepatitis B immune globulin after liver transplantation.
Author	Protzer-Knolle U,Naumann U,Bartenschlager R,Berg T,Hopf U,Meyer zum Büschenfelde KH,Neuhaus P,Gerken G
Evidence	Amino acid exchanges of the polymerase protein were predicted at aa p459, 460, 461, 463,464, 466, 477, and 488 affecting the reverse-transcriptase domain of the HBV polymerase-gene product

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation