HBV Mutation Detail Information

> N236T Search Result


Mutation Information
Mutation Site N236T
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.N236T+rt.A181V;rt.N236T;rt.M204I+rt.M204V+rt.N236T+rt.A181V;rt.N236T+rt.M204I+rt.M204V;rt.M250L+rt.M250I+rt.M250V+rt.S202C+rt.S202G+rt.T184I+rt.T184S+rt.T184A+rt.T184L+rt.T184F+rt.T184G+rt.M204I+rt.M204V+rt.N236T+rt.A181V;rt.N236T+rt.M204V+rt.S202G+rt.L180M;rt.N236T+rt.M204V+rt.T184A+rt.L180M;rt.N236T+rt.M204V+rt.A181V+rt.L180M+rt.L80I
Genotype/Subtype B;C
Relevant Drug Adefovir(ADV)
Country China
Literature Information
PubMed PMID 27792585
Disease HBV infection
Published Year 2017
Journal Microbial drug resistance (Larchmont, N.Y.)
Title Comparison of Detection Rate and Mutational Pattern of Drug-Resistant Mutations Between a Large Cohort of Genotype B and Genotype C Hepatitis B Virus-Infected Patients in North China.
Author Li X,Liu Y,Xin S,Ji D,You S,Hu J,Zhao J,Wu J,Liao H,Zhang XX,Xu D
Evidence For adefovir-resistant mutations, HBV/C-infected patients had a higher detection rate of rtA181 V (HBV/C 5.29% vs. HBV/B 1.36%, p < 0.01) and a lower detection rate of rtN236T (2.70% vs. 6.54%, p < 0.01).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation