HBV Mutation Detail Information

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Mutation Information
Mutation Site V173L
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Viral Reference GQ872210.1
Relevant Drug clevudine (CLV);lamivudine (LAM)
Country korea
Literature Information
PubMed PMID 20164224
Disease Chronic hepatitis B
Published Year 2010
Journal Journal of virology
Title Identification and characterization of clevudine-resistant mutants of hepatitis B virus isolated from chronic hepatitis B patients.
Author Kwon SY,Park YK,Ahn SH,Cho ES,Choe WH,Lee CH,Kim BK,Ko SY,Choi HS,Park ES,Shin GC,Kim KH
Evidence A quadruple mutant (L129M, V173L, M204I, and H337N) was identified that conferred greater replicative ability and strong resistance to both CLV and lamivudine.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation