|
Mutation Information
|
Mutation Site
|
M250V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M250V+rt.M204I+rt.L180M |
|
Relevant Drug
|
entecavir (ETV) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
28017671
|
|
Disease
|
HBV infection
|
|
Published Year
|
2017 |
|
Journal
|
Journal of global antimicrobial resistance |
|
Title
|
Analysis of the prevalence of drug-resistant hepatitis B virus in patients with antiviral therapy failure in a Chinese tertiary referral liver centre (2010-2014). |
|
Author
|
Meng T,Shi X,Gong X,Deng H,Huang Y,Shan X,Shan Y,Huang A,Long Q |
|
Evidence
|
L180M+M204V/I+X (including I169T,T184I/L/G,V207L,S213T,M250V and Q215H) were less prevalent in the ETV resistant cohort. Substitutions in the LdT genotypic resistance cohort were similart othose in the 3TC resistance cohort.
|
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HBV Mutation Detail Information