|
Mutation Information
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Mutation Site
|
M204V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204V+rt.L180M;rt.V173L+rt.M204V+rt.L180M |
|
Genotype/Subtype
|
A;F |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Argentina |
Literature Information
|
PubMed PMID
|
17506609
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2007 |
|
Journal
|
AIDS research and human retroviruses |
|
Title
|
Hepatitis B virus genotype distribution and its lamivudine-resistant mutants in HIV-coinfected patients with chronic and occult hepatitis B. |
|
Author
|
Quarleri J,Moretti F,Bouzas MB,Laufer N,Carrillo MG,Giuliano SF,Pérez H,Cahn P,Salomon H |
|
Evidence
|
These viral strains showed a methionine-to-valine substitution at codon 204 (rtM204V) in association with an upstream B-domain change at rtL180M. Additionally, two of them exhibited the additional rtV173L mutation.
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HBV Mutation Detail Information