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Mutation Information
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Mutation Site
|
N238T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.N238T+rt.M204I+rt.L180M |
|
Relevant Drug
|
lamivudine (LAM);adefovir dipivoxil (ADV);tenofovir (TDF);entecavir (ETV) |
|
Country
|
Vietnam |
Literature Information
|
PubMed PMID
|
32708399
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2020 |
|
Journal
|
Diagnostics (Basel, Switzerland) |
|
Title
|
COLD-PCR Method for Early Detection of Antiviral Drug-Resistance Mutations in Treatment-Naive Children with Chronic Hepatitis B. |
|
Author
|
Phung TTB,Chu SV,Vu ST,Pham HT,Nguyen HM,Nguyen HD,Le NT,Nguyen DV,Truong PT,Vu VTT,Nguyen ATV |
|
Evidence
|
Single-point mt associated to LMV and ADF resistance were detected in 59.9% of the tested children with rtV207M (38.0%) and rtN238T (9.9%) being the most frequent.
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HBV Mutation Detail Information