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Mutation Information
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Mutation Site
|
M204V |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204I+rt.M204V+rt.L180M;rt.S202G+rt.M204I+rt.M204V+rt.L180M;rt.T184A+rt.M204I+rt.M204V+rt.L180M |
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Genotype/Subtype
|
B;C |
|
Country
|
China |
Literature Information
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PubMed PMID
|
29119303
|
|
Disease
|
HBV infection
|
|
Published Year
|
2018 |
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Journal
|
Virus genes |
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Title
|
Evolution of drug-resistant mutations in HBV genomes in patients with treatment failure during the past seven years (2010-2016). |
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Author
|
Zhang HY,Liu LG,Ye CY,Chen CH,Hang SX,Zhu Z,Shen HY,Huang ZY,Chen WY,Xue Y |
|
Evidence
|
Among the primary NA-resistant mutations, rtM204I (13.44%, 545/4055) occurred more frequently, followed by rtM204V, rtN236T, rtA181T, and rtA181V.
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HBV Mutation Detail Information