HBV Mutation Detail Information

> M552I Search Result

Mutation Information

Mutation Site	M552I
Mutation Type	Amino acid level
Gene/Protein/Region Type	P
Genotype/Subtype	C
Relevant Drug	lamivudine (LAM)
Country	China

Literature Information

PubMed PMID	15048802
Disease	Liver cirrhosis
Published Year	2004
Journal	Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
Title	Fibrosing cholestatic hepatitis secondary to precore/core promoter hepatitis B variant with lamivudine resistance: successful retransplantation with combination adefovir dipivoxil and hepatitis B immunoglobulin.
Author	Lo CM,Cheung ST,Ng IO,Liu CL,Lai CL,Fan ST
Evidence	Comparison of the HBV polymerase gene in the 2 serum samples revealed a single mutation with methionine-to-isoleucine substitution at codon 552 (M552I) in both patients.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation