Mutation Information
Mutation Site
|
A186T |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Genotype/Subtype
|
C |
Relevant Drug
|
lamivudine (LAM);entecavir (ETV) |
Country
|
Japan |
Literature Information
PubMed PMID
|
25817219
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2015 |
Journal
|
Journal of hepatology |
Title
|
Characterization of novel entecavir resistance mutations. |
Author
|
Hayashi S,Murakami S,Omagari K,Matsui T,Iio E,Isogawa M,Watanabe T,Karino Y,Tanaka Y |
Evidence
|
Here, we characterized two novel mutations, rtI163V and rtA186T, associated with viral breakthrough (VBT) in an ETV-refractory patient.
|
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