HBV Mutation Detail Information

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Mutation Information

Mutation Site	S202G
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	rt.M204V+rt.S202G+rt.L180M;rt.M204V+rt.S202G+rt.A181G+rt.L180M;rt.M204V+rt.S202G+rt.L180M+rt.P177S+rt.V173L;rt.M204V+rt.S202G+rt.I169L+rt.L180M
Relevant Drug	lamivudine (LAM);entecavir (ETV)

Literature Information

PubMed PMID	17239478
Disease	Chronic hepatitis B; Liver cirrhosis
Published Year	2007
Journal	Journal of hepatology
Title	Stepwise process for the development of entecavir resistance in a chronic hepatitis B virus infected patient.
Author	Villet S,Ollivet A,Pichoud C,Barraud L,Villeneuve JP,Trépo C,Zoulim F
Evidence	Three years later, the viral load rose again, and a complex mixture of entecavir-resistant strains, all harboring the lamivudine-resistance signature rtL180M+M204V and the rtS202G mutation were observed.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation